NGFR/p75 neurotrophin receptor (p75NTR) Antibody (Saporin)

SKU: orb3167455

Description

Our Anti-NGFR/p75 neurotrophin receptor (p75NTR) mouse monoclonal primary antibody detects rat NGFR/p75 neurotrophin receptor (p75NTR), and is purified. It is validated for use in-vivo.

Images & Validation

• Tested Applications: In vivo
• Reactivity: Rat
• Application Notes:
  1. To specifically target and eliminate rat cells expressing p75NTR in vivo. MC192-saporin has been used to selectively lesion cholinergic neurons of basal forebrain to create an animal model to study Alzheimer's disease. 2. To be used as a model for gene delivery into neurons.

Key Properties

• Host: Mouse
• Clonality: Monoclonal
• Isotype: IgG1
• Clone No.: MC192
• Immunogen: Rat NGF receptor (p75NTR)
• Target: NGFR/p75 neurotrophin receptor (p75NTR)
• Purification: Purified
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: Lyophilized
• Buffer/Preservatives: Lyophilized from a 1 mg/mL solution containing PBS pH 7.2-7.6 without preservative.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Low-affinity nerve growth factor receptor; NGF receptor; Gp80-LNGFR; p75 ICD; Low affinity neurotrophin receptor p75NTR; CD271

Quick Database Links

Gene Symbol

NGFR/p75 neurotrophin receptor (p75NTR)

UniProt

P20656, P07174