NGF-Receptor (p75) / CD271 (Soft Tissue Tumor Marker) Antibody

SKU: orb1410062

Description

Mouse monoclonal antibody to NGF-Receptor (p75)

Images & Validation

• Tested Applications: IF, IHC, WB
• Reactivity: Human

Key Properties

• Host: Mouse
• Clonality: Monoclonal
• Isotype: IgG1
• Clone No.: NGFR/4919
• Immunogen: WM245 melanoma cells of human origin.
• Target: NGFR
• Source/Expression System: Bioreactor
• Molecular Weight: 75kDa
• Purification: Protein G

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% rAlbumin & 0.05% azide. Also available WITHOUT rAlbumin & azide at 1.0mg/ml.
• Disclaimer: For research use only

Alternative Names

CD271; Gp80-LNGFR; Low affinity nerve growth factor receptor; Low affinity neurotrophin receptor p75NTR; p75 ICD; p75 Neurotrophin receptor; Tumor necrosis factor receptor superfamily member 16 (TNFRSF16)

Analysis of Protein Array containing more than 19000 full-length human proteins using NGFR-Monospecific Mouse Monoclonal Antibody (NGFR/4919). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.

Formalin-fixed, paraffin-embedded human melanoma stained with NGFR Mouse Monoclonal Antibody (NGFR/4919) at 2 ug/ml. HIER: Tris/EDTA, pH9.0, 45 min. 2°C: HRP-polymer, 30 min. DAB, 5 min.

Formalin-fixed, paraffin-embedded human melanoma stained with NGFR Mouse Monoclonal Antibody (NGFR/4919) at 2 ug/ml. Inset: PBS instead of primary antibody; secondary only negative control.

SDS-PAGE Analysis of Purified NGFR Mouse Monoclonal Antibody (NGFR/4919). Confirmation of Purity and Integrity of Antibody.

Quick Database Links

Gene Symbol

NGFR

UniProt

P08138