NFAT Inhibitor

SKU: orb1296794

Description

The VIVIT peptide is a cell-permeable inhibitor that selectively blocks calcineurin from dephosphorylating NFAT. This tool compound is widely used in vitro and in vivo to study NFAT signaling in immunology, neuroscience, and cardiac hypertrophy research.

Research Area

Pharmacology & Drug Discovery

Key Properties

• Target: Others
• CAS Number: 249537-73-3
• MW: 1683.93
• Purity: 98.26% (May vary between batches)
• Formula: C₇₅H₁₁₈N₂₀O₂₂S
• SMILES: CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](C)NC(=O)[C@@H](N)CCSC)C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(O)=O

Storage & Handling

• Storage: keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

TRAP, testosterone, VIVIT peptide, dephosphorylation, cell-permeable, cathepsin-K, alcineurin, Nuclear factor of activated Tcells (NFAT), NFAT Inhibitor, NFAT Inhibitor 1, NFAT Inhibitor1, NFAT Inhibitor-1, NFAT, NFAT-Luc, MMP‐9, inhibit, Inhibitor

Compound Identifiers

PubChem CID

16135717