Nefopam hydrochloride

SKU: orb1310581

Description

Nefopam hydrochloride is the HCl salt form of nefopam, a centrally-acting, non-opioid analgesic of the benzoxazocine class. It is utilized in research to investigate pain mechanisms, with studies demonstrating its efficacy in various in vivo pain models and its action on monoamine reuptake in vitro.

Research Area

Pharmacology & Drug Discovery, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 23327-57-3
• MW: 289.8
• Purity: 99.97% (May vary between batches)
• Formula: C₁₇H₂₀ClNO
• SMILES: Cl.CN1CCOC(c2ccccc2)c2ccccc2C1
• Target: Wnt/beta-catenin,Sodium Channel
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (3.45 mM);DMSO:4.62 mg/mL (15.94 mM)

Bioactivity

• In Vitro:
  The mechanism of action through which nefopam exerts its analgesic effects is, as of yet, largely unknown but may involve inhibition of serotonin, dopamine and noradrenaline reuptake.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

inhibit, Nefopam, Nefopam HCl, Nefopam hydrochloride, Nefopam Hydrochloride, Fenazoxine, Fenazoxine hydrochloride, Fenazoxine Hydrochloride, Inhibitor, bcatenin, Beta catenin, betacatenin, beta-catenin, Wnt, Wnt/β-catenin, Wnt/b-catenin, Wnt/betacatenin, Sodium Channel, SodiumChannel, β-catenin, βcatenin

Compound Identifiers

PubChem CID

155290