Nefopam hydrochloride

SKU: orb1225568

Description

Nefopam hydrochloride is a centrally-acting but non-opioid analgesic drug by blocking voltage-gated sodium channel and inhibition of serotonin, dopamine and noradrenaline reuptake.(In Vitro):Nefopam hydrochloride (Fenazoxine hydrochloride) is a non-opioid, non-steroidal, centrally acting analgesic drug that is derivative of the non-sedative benzoxazocine. Constitutively elevated β-catenin leads to a delayed and fibrous fracture repair process, and Nefopam inhibits β-catenin mediated signaling during skin wound repair.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 23327-57-3
• MW: 289.8
• Purity: >98% (HPLC)
• Formula: C₁₇H₂₀ClNO
• SMILES: Cl.CN1CCOC(C2=CC=CC=C2)C2=CC=CC=C2C1
• Target: Sodium Channel
• Solubility: Water: 21 mg/mL (72.46 mM); DMSO: 1 mg/mL (3.45 mM)

Bioactivity

• In Vitro:
  Nefopam hydrochloride (Fenazoxine hydrochloride) is a non-opioid, non-steroidal, centrally acting analgesic drug that is derivative of the non-sedative benzoxazocine. Constitutively elevated β-catenin leads to a delayed and fibrous fracture repair process, and Nefopam inhibits β-catenin mediated signaling during skin wound repair.
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Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Sodium Channel