NDI-101150

SKU: orb2646017

Description

NDI-101150 (NMBS-2) is a potent, selective, and orally bioavailable HPK1 inhibitor that blocks BLNK phosphorylation. Its application in cancer research includes investigating mechanisms for enhancing anti-tumor immunity, with studies conducted in both cellular assays and preclinical in vivo models of metastatic solid tumors.

Research Area

Signal Transduction

Key Properties

• CAS Number: 2628486-22-4
• MW: 486.54
• Purity: 99.65% (May vary between batches)
• Formula: C₂₇H₂₇FN₆O₂
• SMILES: N(C1=C2C(=C(C=C1)C=3N4C(=NC3)C=C(F)C=C4)CNC2=O)C=5N=C(CN(C)C)C(=CC5)[C@@H]6CCOC6
• Target: Others,MAPK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

NDI101150, NMBS2, NMBS-2

Compound Identifiers

PubChem CID

156152735