Nanatinostat TFA

SKU: orb1738370

Description

Nanatinostat (CHR-3996) is an oral, second-generation HDAC inhibitor with antineoplastic potential. It promotes histone hyperacetylation and gene expression changes leading to cell cycle arrest and apoptosis, showing enhanced effects on HSP70 and Bcl-2 compared to earlier inhibitors. It has been investigated in preclinical models for hematological and solid tumors.

Research Area

Cell Biology, Epigenetics & Chromatin, Immunology & Inflammation, Molecular Biology

Key Properties

• CAS Number: 1256448-48-2
• MW: 508.43
• Formula: C₂₂H₂₀F₄N₆O₄
• SMILES: OC(=O)C(F)(F)F.[H][C@@]12CN(C[C@]1([H])[C@H]2NCc1ccc2cc(F)ccc2n1)c1ncc(cn1)C(=O)NO
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

131888677