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N-piperidine Ibrutinib

SKU: orb1298112

Description

N-piperidine Ibrutinib

Research Area

Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

Key Properties

CAS Number330785-90-5
MW386.45
Purity96.65% (May vary between batches)
FormulaC22H22N6O
SMILESNC1=C2C(=NN(C2=NC=N1)C3CCNCC3)C4=CC=C(OC5=CC=CC=C5)C=C4
TargetBTK,Ligands for Target Protein for PROTAC

Bioactivity

In Vitro
N-piperidine Ibrutinib can be used as a BTK ligand in the synthesis of a series of PROTACs. SJF638, SJF678, and SJF608 are potent PROTAC BTK degraders with DC50s of 374, 162, and 8.3 nM, respectively.

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

BTK, N piperidine Ibrutinib, Npiperidine Ibrutinib, N-piperidine Ibrutinib

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Key Properties

No computed properties available.

Protocol Information

Available Sizes

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1 mg
$ 80.00
5 mg
$ 130.00
10 mg
$ 170.00
25 mg
$ 240.00
50 mg
$ 330.00
100 mg
$ 420.00
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