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N-Nornuciferine hydrochloride

N-Nornuciferine hydrochloride

Catalog Number: orb1219447

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Catalog Numberorb1219447
CategorySmall Molecules
DescriptionN-Nornuciferine is an aporphine alkaloid in lotus leaf, significantly inhibits CYP2D6 (IC50: 3.76 μM, Ki: 2.34 μM).N-Nornuciferine strongly inhibits CYP2D6 activity but shows weak or no inhibition of the other four P450 isoenzymes (CYP2C19, CYP3A4, CYP2E1, CYP2C9). N-Nornuciferine competitively inhibits the CYP2D6-catalyzed dextromethorphan O-demethylation (Ki: 2.34 μM).
CAS Number——
Purity> 98% (HPLC)
MW——
Formula——
TargetCYP2D6
StorageStorage temperature: -20°C. Stability: ≥ 2 years
NoteFor research use only
Expiration Date12 months from date of receipt.