N-Formyl-Met-Leu-Phe-Lys

• Catalog Number: orb1296725
• Category: Small Molecules
• Description: N-Formyl-Met-Leu-Phe-Lys
• CAS Number: 67247-11-4
• Purity: 99.70%
• MW: 565.73
• SMILES: [C@@H](CC1=CC=CC=C1)(NC([C@@H](NC([C@H](CCSC)NC=O)=O)CC(C)C)=O)C(N[C@@H](CCCCN)C(O)=O)=O
• Formula: C₂₇H₄₃N₅O₆S
• Biological Activity: N-Formyl-Met-Leu-Phe-Lys (fMLFK) (fMLFK) is a peptide, acts as a potent and selective agonist of FPR1, with EC50s of 3.5 nM, 6.7 μM and 0.88 μM for FPR1, FPR2 and FPR2-D2817.32G, respectively.Chemotactic peptide (fMLFK) binds specifically to receptors on leukocyte membranes. Uptake of chemotactic peptides can contribute to quantitative assessment of neutrophils in localized inflammatory processes and is independent of associated edema formation or microcirculatory compromise.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.