N-Formyl-Met-Leu-Phe-Lys

SKU: orb1219865

Description

N-Formyl-Met-Leu-Phe-Lys (fMLFK) is a peptide, acts as a potent and selective agonist of FPR1, with EC50s of 3.5 nM, 6.7 μM and 0.88 μM for FPR1, FPR2 and FPR2-D2817.32G, respectively.Chemotactic peptide (fMLFK) binds specifically to receptors on leukocyte membranes. Uptake of chemotactic peptides can contribute to quantitative assessment of neutrophils in localized inflammatory processes and is independent of associated edema formation or microcirculatory compromise.

Research Area

Cell Biology

Images & Validation

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Key Properties

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CAS Number	67247-11-4
MW	565.73
Purity	>98% (HPLC)
Formula	C₂₇H₄₃N₅O₆S
Target	FPR1\|FPR2
Solubility	H2O

Storage & Handling

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Storage	Storage temperature: -20°C. Stability: ≥ 2 years
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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fMLFK

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Quick Database Links

Gene Symbol

FPR1|FPR2

Protocol Information

Find More Protocols

Purity:	≥95%
CAS Number:	104180-18-9
MW:	565.74
Formula:	C₂₇H₄₃N₃O₆S

Purity:	> 95%
MW:	565.74
Source:	Synthetic

Purity:	99.70% (May vary between batches)
MW:	565.73

Purity:	≥95%
MW:	565.74