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N-Acetylgalactosaminyltransferase 4

SKU: orb3142895

Description

N-Acetylgalactosaminyltransferase 4 (GALNT4) is a glycosyltransferase capable of inhibiting the activation of ASK1. It functions by directly binding to ASK1, preventing N-terminal dimerization and subsequent phosphorylation. This interaction leads to significant inactivation of downstream JNK/p38 and NF-κB signaling, thereby improving the prognosis of liver surgery.

Research Area

Metabolism Research, Signal Transduction

Images & Validation

Key Properties

TargetEndogenous Metabolite,JNK,MAPK,p38 MAPK,NF-κB

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information