Myelin PLP Antibody

• Catalog Number: orb699747
• Category: Antibodies
• Description: Proteolipid protein (PLP) is the major myelin protein of the CNS and plays an important role in the formation and maintenance of myelin. PLP may play a role in the compaction and stabilization of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in PLP gene can lead to dysmyelinating diseases.
• Species/Host: Mouse
• Clonality: Monoclonal
• Clone Number: PLP1/4259
• Tested applications: IHC-P
• Reactivity: Human
• Isotype: Mouse IgG2a
• Immunogen: A synthetic peptide from the C terminal region of the human protein was used as the immunogen for the Myelin PLP antibody. The epitope has been mapped to amino acids GRGTKF.
• Dilution range: Immunohistochemistry (FFPE): 1-2ug/ml for 30 minutes at RT
• Purity: Protein G affinity chromatography
• Conjugation: Unconjugated
• Formula: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
• Hazard Information: This Myelin PLP antibody is available for research use only.
• UniProt ID: P60201
• Storage: Store the Myelin PLP antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
• Buffer/Preservatives: 0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin (US sourced), 0.05% sodium azide
• Note: For research use only
• Application notes: Optimal dilution of the Myelin PLP antibody should be determined by the researcher.
• Expiration Date: 12 months from date of receipt.