Mycro 3

SKU: orb1302914

Description

Mycro 3 is a potent and selective small molecule inhibitor of the c-Myc oncoprotein. It is a valuable research tool for investigating c-Myc's role in cancer biology and cellular proliferation in both in vitro and in vivo experimental models.

Research Area

Cell Biology

Key Properties

• CAS Number: 944547-46-0
• MW: 526.88
• Purity: 97.87% (May vary between batches)
• Formula: C₂₄H₁₇ClF₂N₆O₄
• SMILES: CCOC(=O)c1cnn(c1NC(=O)c1cc2nc(cc(n2n1)C(F)(F)Cl)-c1ccco1)-c1ccccc1
• Target: Autophagy,c-Myc
• Solubility: DMSO:55 mg/mL (104.39 mM);10% DMSO+90% Corn Oil:2.5 mg/mL (4.74 mM)

Bioactivity

• In Vitro:
  Mycro 3 inhibits the interaction between c-Myc and Max. Mycro 3 has high selectivity and inhibits c-Myc/Max dimerization and conjugation with DNA. Mycro 3 is potent and selective for c-Myc in whole cell assays, with weak inhibitory activity against Activator protein 1 (AP-1), Mycro 3 has a superior specificity profile to its predecessors.
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

pancreatic, Mycro 3, Mycro3, Mycro-3, Myc, inhibit, PDA, Inhibitor, MAX, dimerization, ductal, c-Myc, cMyc, adenocarcinoma, Autophagy

Compound Identifiers

PubChem CID

1045147