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Mycro-3

SKU: orb1222976

Description

Mycro3 is an inhibitor of Myc-Max dimerization.

Images & Validation

Key Properties

CAS Number944547-46-0
MW526.88
Purity>98% (HPLC)
FormulaC24H17ClF2N6O4
SMILESCCOC(=O)c1c(n(nc1)c1ccccc1)NC(=O)c1nn2c(cc(nc2c1)c1ccco1)C(F)(F)Cl
Targetc-Myc
SolubilityDMSO : ≥ 100 mg/mL; 189.80 mM

Bioactivity

In Vivo
Animal model: Moribund Pdx1-cre/KRAS* mice bearing pancreatic ductal adenocarcinoma (PDA). Dosage: 100 mg/kg. Administration: Oral administration; daily for two months. Result: Increased survival time. Mycro 3 administration was discontinued after two months, the mouse survived for an additional month.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Mycro3 | Mycro-3 | Mycro 3

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  • Mycro 3 [orb1302914]

    97.87% (May vary between batches)

    944547-46-0

    526.88

    C24H17ClF2N6O4

    100 mg, 1 ml x 10 mM (in DMSO), 200 mg, 1 mg, 5 mg, 10 mg, 25 mg, 50 mg
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Protocol Information

Mycro-3 (orb1222976)

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Available Sizes

Select a size below

2 mg
$ 190.00
5 mg
$ 280.00
10 mg
$ 470.00
25 mg
$ 920.00
50 mg
$ 1,300.00
100 mg
$ 1,790.00
500 mg
$ 3,570.00