Musk ketone

SKU: orb1220805

Description

Musk ketone can induce the growth repression and the apoptosis of cancer cells. Musk ketone increases activity of glutathione S-transferase and thus may prove to be useful cancer chemoprotectant.

Research Area

Signal Transduction

Key Properties

• CAS Number: 81-14-1
• MW: 294.3
• Purity: >98% (HPLC)
• Formula: C₁₄H₁₈N₂O₅
• SMILES: CC(=O)c1c(C)c(c(c(c1C)[N+]([O-])=O)C(C)(C)C)[N+]([O-])=O
• Target: Others
• Solubility: In Vitro: DMSO : ≥ 125 mg/mL (424.74 mM)

Bioactivity

• In Vitro:
  Apoptosis Analysis Cell line: AGS, HGC-27. Concentration: 4.2 μM for AGS, 10.06 μM for HGC-27 Incubation time: 48 h. Result: Increased ratio of Cle-caspase 3 to caspase 3 protein level. Induced cell apoptosis, detected by PI/Annexin V staining;
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Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Others