Queen's Award Received in 2021 ISO 9001 Certified Delivered over 1,000,000 bio-reagents to life science researchers Trusted by Life Science Communities
Cart summary

You have no items in your shopping cart.

MT-44

SKU: orb3173716

Description

MT-44 is a highly selective and potent mTOR inhibitor with an IC50 value of 49.4 nM. It inhibits the proliferation, migration, and invasion of cancer cells. MT-44 induces apoptosis (apoptosis) and reactive oxygen species (ROS) production, leading to G2/M phase arrest. Additionally, it activates the cGAS/STING pathway. MT-44 is applicable in cancer research, including studies on triple-negative breast cancer.

Images & Validation

Key Properties

CAS Number2966790-70-3
MW469.5
FormulaC26H23N5O4
SMILESN(=C\1/C=2C(OC(=C1)C=3C=C4C(=CC3)N=C(N)O4)=CC=C(OC)C2)\C5=C(NC(CCN)=O)C=CC=C5
TargetSTING,Apoptosis,mTOR,ROS

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Similar Products

  • SHMT2-IN-1 [orb3173831]

    50 mg, 10 mg
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Documents Download

Datasheet
Product Information
Download

Request a Document

Protocol Information

MT-44 (orb3173716)

  • Star
  • Star
  • Star
  • Star
  • Star
  • 0.0
Based on 0 reviews

Participating in our Biorbyt product reviews program enables you to support fellow scientists by sharing your firsthand experience with our products.

Login to Submit a Review

No reviews yet

Step 1: Enter information below

(Recommended: An additional animal making an allowance for loss during the experiment)

Step 2: Enter the in vivo formulation

(This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO +
%+
% Tween 80 +
%