MT-44

SKU: orb3173716

Description

MT-44 is a highly selective and potent mTOR inhibitor with an IC50 value of 49.4 nM. It inhibits the proliferation, migration, and invasion of cancer cells. MT-44 induces apoptosis (apoptosis) and reactive oxygen species (ROS) production, leading to G2/M phase arrest. Additionally, it activates the cGAS/STING pathway. MT-44 is applicable in cancer research, including studies on triple-negative breast cancer.

Research Area

Cell Biology, Immunology & Inflammation, Signal Transduction

Key Properties

• CAS Number: 2966790-70-3
• MW: 469.5
• Formula: C₂₆H₂₃N₅O₄
• SMILES: N(=C\1/C=2C(OC(=C1)C=3C=C4C(=CC3)N=C(N)O4)=CC=C(OC)C2)\C5=C(NC(CCN)=O)C=CC=C5
• Target: STING,Apoptosis,ROS,mTOR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

STING,Apoptosis,ROS,mTOR