You have no items in your shopping cart.
Cart summary
MRK-016
Catalog Number: orb2893738
Product Properties
| Catalog Number | orb2893738 |
|---|---|
| Category | Small Molecules |
| Description | MRK-016 is a selective GABAA α5 receptor inverse agonist/ negative allosteric modulator, (IC50=3 nM) with the advantages of being orally available and penetrating the blood-brain barrier.MRK-016 increases long time period potentiation (LTP) in mouse hippocampal slices, with memory-improvement, antidepressant, and pain-treating effects. |
| Target | GABA Receptor |
| Purity | 99.76% |
| MW | 368.39 |
| CAS Number | 342652-67-9 |
| Formula | C17H20N8O2 |
| SMILES | N=1N=C(C2=NOC(=C2)C)N3N=C(OCC4=NC=NN4C)C(=C3C1)C(C)(C)C |
| Storage | -20°C |
| Research Area | Neuroscience, Pharmacology & Drug Discovery |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
Images
Similar Products
Reviews
MRK-016 (orb2893738)
- 0.0
Based on 0 reviews
Participating in our Biorbyt product reviews program enables you to support fellow scientists by sharing your firsthand experience with our products.
Login to Submit a Review Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Step 1: Enter information below
(Recommended: An additional animal making an allowance for loss during the experiment)
Step 2: Enter the in vivo formulation
(This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
% DMSO +
%+
% Tween 80 +
%
