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MPS1/TTK Inhibitor

SKU: orb1693209

Description

This small molecule is a potent and selective MPS1/TTK kinase inhibitor (IC50 = 5.8 nM) that disrupts the spindle assembly checkpoint, leading to chromosome missegregation and inhibited colony formation in cancer cell lines. Its application is primarily in cell biology and oncology research for studying mitosis, aneuploidy, and as a potential chemotherapeutic agent in preclinical models.

Research Area

Neuroscience; Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number1202055-39-7
MW580.72
FormulaC33H40N8O2
SMILESCN1C=2C=3C(CCC2C(C(NC4=C(CC)C=CC=C4CC)=O)=N1)=CN=C(NC5=C(OC)C=C(C=C5)N6CCN(C)CC6)N3
TargetOthers

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information