Mouse LIF protein

SKU: orb670333

Description

LIF (leukemia inhibitory factor) is a widely expressed pleiotropic member of the IL-6 family of cytokines. The protein encoded by this gene is a pleiotropic cytokine with roles in several different systems. It is involved in the induction of hematopoietic differentiation in normal and myeloid leukemia cells, induction of neuronal cell differentiation, regulator of mesenchymal to epithelial conversion during kidney development, and may also have a role in immune tolerance at the maternal-fetal interface. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Key Properties

• Source: E. coli Ser24-Phe203
• Target: LIF
• Reactivity: Mouse
• Molecular Weight: 19.8KD
• Protein Sequence: SPLPI TPVNA TCAIR HPCHG NLMNQ IKNQL AQLNG SANAL FISYY TAQGE PFPNN VEKLC APNMT DFPSF HGNGT EKTKL VELYR MVAYL SASLT NITRD QKVLN PTAVS LQVKL NATID VMRGL LSNVL CRLCN KYRVG HVDVP PVPDH SDKEA FQRKK LGCQL LGTYK QVISV VVQAF
• Purification: >95%, by SDS-PAGE quantitative densitometry by Coomassie? Blue Staining.
• Endotoxins: Less than 1 EU/μg of LIF as determined by LAL method.

Storage & Handling

• Storage: Lyophilized recombinant Mouse Leukemia Inhibitory Factor remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, rmLIF remains stable up to 2 weeks at 4°C or up to 3 months at -20°C.
• Form/Appearance: Lyophilized
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

LIF

UniProt

P15018