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Montelukast

SKU: orb1307785

Description

Montelukast is a leukotriene receptor antagonist used in asthma research. It is widely applied in both in vivo and in vitro studies to investigate inflammatory pathways and has been associated with rare instances of drug-induced liver injury in clinical reports.

Research Area

Immunology & Inflammation, Metabolism Research, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number158966-92-8
MW586.18
Purity98.00% (May vary between batches)
FormulaC35H36ClNO3S
SMILESCC(C)(O)c1ccccc1CC[C@@H](SCC1(CC(O)=O)CC1)c1cccc(\C=C\c2ccc3ccc(Cl)cc3n2)c1
TargetLTR,Leukotriene Receptor,Lipoxygenase
Solubility10% DMSO+90% Corn Oil:5 mg/mL (8.53 mM);H2O:1.7 mM;DMSO:250 mg/mL (426.49 mM)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

antioxidant, asthma, ALOX5, COVID-19, Cysltr1, CysLTR1, cysteinyl, damage, icardiac, Inhibitor, injury, leukotriene, Leukotriene Receptor, LeukotrieneReceptor, ischemia–reperfusion, Montelukast, intestinal, inhibit, liver, MK0476, MK-0476, MK 0476, Singular

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Key Properties

No computed properties available.

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Montelukast (orb1307785)

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(Recommended: An additional animal making an allowance for loss during the experiment)

Step 2: Enter the in vivo formulation

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