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MMS21 (N) Antibody, Rabbit Polyclonal
Catalog Number: orb67031
| Catalog Number | orb67031 |
|---|---|
| Category | Antibodies |
| Description | Rabbit polyclonal to MMS21.MMS21 is also known as E3 SUMO-protein ligase NSE2E3, which is a SUMO-protein ligasecomponent of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks byhomologous recombination. The complex may promote sister chromatid homologous recombinationby recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. MMS21 acts as a E3 ligasemediating SUMO attachment to various proteins such as SMC6L1 and TRAX, and maybe the cohesincomponents RAD21 and STAG2. The SUMO protein-ligase activity of MMS21 is required for theprevention of DNA damage-induced apoptosis by facilitating DNA repair. |
| Clonality | Polyclonal |
| Species/Host | Rabbit |
| Conjugation | Unconjugated |
| Reactivity | Human |
| Buffer/Preservatives | 0.01% NaN3 |
| Purity | Affinity purification |
| Immunogen | N-terminal region of human MMS21 |
| UniProt ID | Q96MF7 |
| MW | 28 |
| Tested applications | WB |
| Dilution range | WB:1:1000-1:5000 |
| Storage | -20°C |
| Alternative names | anti-MMS21 antibody,anti-E3 SUMOprotein ligase NSE Read more... |
| Note | For research use only |
Western blot analysis of total cell extracts from human MCF7 using MMS21 antibody
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