MMP-9-IN-1

SKU: orb1299049

Description

MMP-9-IN-1 is a selective small molecule inhibitor of matrix metalloproteinase-9 (MMP-9). It is a valuable research tool for studying MMP-9's role in cancer metastasis, inflammation, and tissue remodeling in both cellular and animal models.

Research Area

Cancer Biology; Musculoskeletal & Connective Tissue Research, Protein Biochemistry

Key Properties

• CAS Number: 502887-71-0
• MW: 369.39
• Purity: 99.91% (May vary between batches)
• Formula: C₁₆H₁₇F₂N₃O₃S
• SMILES: CCCc1cc(=O)[nH]c(SCC(=O)Nc2ccc(OC(F)F)cc2)n1
• Target: MMP
• Solubility: DMSO:125 mg/mL (338.4 mM);10% DMSO+90% Corn Oil:3.3 mg/mL (8.93 mM)

Bioactivity

• In Vitro:
  MMP-9-IN-1 inhibits tumor growth and metastasis by reducing cell migration and proliferation.
• Cell Research:
  Cell Line:HT-1080 and MDA-MB-435 cancer cells expressing endogenous MMP-9. Concentration:10 μM.Incubation Time:9 days

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

PEX, tumor, inhibit, MMP, MMP 9 IN 1, MMP9IN1, MMP-9-IN-1, MMP-9, lung, metastasis, Matrix metalloproteinases, Inhibitor, hemopexin, cancer, anti-metastatic

Compound Identifiers

PubChem CID

135415473