ML221

• Catalog Number: orb1302896
• Category: Small Molecules
• Description: ML221
• CAS Number: 877636-42-5
• Purity: 97.74%
• MW: 385.35
• SMILES: [O-][N+](=O)C1=CC=C(C=C1)C(=O)OC1=COC(CSC2=NC=CC=N2)=CC1=O
• Formula: C₁₇H₁₁N₃O₆S
• Biological Activity: ML221 is a potent apelin /APJ functional antagonist, inhibiting apelin-13-mediated activation of APJ, with IC50s of 0.70 μM in the cAMP assay, and 1.75 μM in the β-arrestin assay, and EC80 of 10 nM in both assays.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.