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ML 254

SKU: orb1218824

Description

ML254 competitively interacts with the MPEP allosteric binding site. ML254 is highly selective for mGlu5 versus other mGlu receptors, has a clean ancillary Ricerca profile, and suitable dystrophia myotonica protein kinase (DMPK) properties for systemic dosing in rodents.

Images & Validation

Key Properties

CAS Number1428630-86-7
MW310.32
Purity>98% (HPLC)
FormulaC18H15FN2O2
SMILESCC1(COC1)NC(=O)C2=NC=C(C=C2)C#CC3=CC(=CC=C3)F
TargetGluR
SolubilityDMSO:10 mM

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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  • ML 254 [orb1298573]

    98.09% (May vary between batches)

    1428630-86-7

    310.32

    C18H15FN2O2

    5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 1 ml x 10 mM (in DMSO)
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Protocol Information

Available Sizes

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500 mg
200 mg
5 mg
$ 210.00
10 mg
$ 320.00
25 mg
$ 710.00
50 mg
$ 1,040.00
100 mg
$ 1,480.00