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MKRN1 (N) Antibody, Rabbit Polyclonal
Catalog Number: orb67218
| Catalog Number | orb67218 |
|---|---|
| Category | Antibodies |
| Description | Rabbit polyclonal to MKRN1.E3 ubiquitin-protein ligase makorin-1 (MKRN1) catalyzes the covalent attachment of ubiquitin moietiesonto substrate proteins. These substrates include FILIP1, p53/TP53, CDKN1A and TERT. MKRN1supports cell survival by suppressing p53/TP53 under normal conditions, but stimulates apoptosis byrepressing CDKN1A under stress conditions. MKRN1 acts as a negative regulator of telomerase andhas negative and positive effects on RNA polymerase II-dependent transcription. |
| Species/Host | Rabbit |
| Clonality | Polyclonal |
| Tested applications | WB |
| Reactivity | Human, Mouse |
| Immunogen | N-terminal region of human MKRN1 |
| Dilution range | WB:1:500-1:2000 |
| Purity | Affinity purification |
| Conjugation | Unconjugated |
| MW | 53 |
| UniProt ID | Q9UHC7 |
| Storage | -20°C |
| Buffer/Preservatives | 0.01% NaN3 |
| Alternative names | anti-MKRN1 antibody,anti-E3 ubiquitinprotein ligas Read more... |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
Western blot analysis of total cell extracts from human Jurkat(Lane1)
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