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MK-2206

SKU: orb1687434

Description

MK-2206 is a potent, selective allosteric Akt inhibitor active against Akt1, Akt2, and Akt3 isoforms. It demonstrates anti-proliferative effects in vitro, particularly in breast cancer models with PIK3CA mutations or PTEN loss, and has been evaluated in preclinical in vivo tumor studies.

Research Area

Cell Biology, Signal Transduction

Images & Validation

Key Properties

CAS Number1032349-77-1
MW443.94
FormulaC25H22ClN5O
SMILESCl.NC1(CCC1)c1ccc(cc1)-c1nc2ccn3c(n[nH]c3=O)c2cc1-c1ccccc1
TargetAutophagy,Others,Akt,Apoptosis

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

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MK-2206 (orb1687434)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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