MK-2206 free base

• Catalog Number: orb1942981
• Category: Small Molecules
• Description: MK-2206 free base is a potent, selective, and orally administered allosteric Akt inhibitor with IC50 values of 8, 12, and 65 nM for Akt1, Akt2, and Akt3, respectively. It demonstrates sensitivity in various breast cancer cell lines, including those with PIK3CA mutations and PTEN loss, indicating its potential for anticancer activities.
• Target: Akt
• MW: 407.47
• CAS Number: 1032349-93-1
• Formula: C₂₅H₂₁N₅O
• SMILES: O=C1NN=C2C=3C=C(C=4C=CC=CC4)C(=NC3C=CN12)C=5C=CC(=CC5)C6(N)CCC6
• Storage: -20°C
• Research Area: Signal Transduction
• Note: For research use only
• Expiration Date: 12 months from date of receipt.