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Microtubule inhibitor 12

SKU: orb2814156

Description

Microtubule inhibitor 12 (Compound 2k) is a potent anti-proliferative agent that disrupts microtubule dynamics (IC50 = 22.23 μM), leading to G2/M phase arrest, apoptosis, and inhibited migration in cancer cells. It shows low micromolar IC50 values against multiple cancer cell lines (B16-F10, A549, HepG2, MCF-7) and exhibits in vivo antitumor activity in mouse models.

Research Area

Cell Biology, Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

Key Properties

MW390.44
FormulaC22H22N4O3
TargetMicrotubule Associated,Apoptosis

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information