MF-438

SKU: orb1308045

Description

MF-438 is a potent and orally bioavailable small molecule inhibitor of stearoyl-CoA desaturase 1 (SCD1), demonstrating an EC50 of 2.3 nM against the rat enzyme. This tool compound is widely used in metabolic disease, cancer, and lipid metabolism research, enabling the investigation of SCD1 function in both cellular and animal models.

Research Area

Cancer Biology, Neuroscience

Key Properties

• CAS Number: 921605-87-0
• MW: 421.44
• Purity: >98%
• Formula: C₁₉H₁₈F₃N₅OS
• SMILES: Cc1nnc(s1)-c1ccc(nn1)N1CCC(CC1)Oc1ccccc1C(F)(F)F
• Target: ER/Golgi
• Solubility: Soluble in DMSO (up to 5 mg/ml) or in Ethanol (up to 2 mg/ml with warming).

Bioactivity

• Target IC50:
  SCD1 (rat):2.3 nM (EC50)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

MF438, MF-438, MF 438, inhibit, Inhibitor, rSCD1, SCD, StearoylCoA Desaturase (SCD), Stearoyl-CoA Desaturase, StearoylCoADesaturase(SCD), StearoylCoADesaturase, Stearoyl-CoA Desaturase (SCD)

Compound Identifiers

PubChem CID

16042458