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MF-438

SKU: orb1219691

Description

MF-438 is an effective and orally bioavailable stearoyl-CoA desaturase 1 (SCD1) inhibitor (EC50: 2.3 nM for rSCD1). In a mouse model, MF-438 shows an ED50 between 1 and 3 mg/kg.

Images & Validation

Key Properties

CAS Number921605-87-0
MW421.44
Purity>98% (HPLC)
FormulaC19H18F3N5OS
SMILESCc1nnc(s1)-c1ccc(nn1)N1CCC(CC1)Oc1ccccc1C(F)(F)F
TargetDehydrogenase
SolubilityDMSO:62.5 mg/mL (148.30 mM; Need ultrasonic)

Bioactivity

In Vivo
MF-438 exhibits an ED50 between 1 and 3 mg/kg in a mouse model.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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  • MF-438 [orb1308045]

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    921605-87-0

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    C19H18F3N5OS

    25 mg, 5 mg
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Protocol Information

Available Sizes

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2 mg
$ 250.00
5 mg
$ 370.00
10 mg
$ 550.00
25 mg
$ 910.00
50 mg
$ 1,300.00
100 mg
$ 1,790.00
500 mg
$ 3,550.00