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Methimazole

SKU: orb1310244

Description

Methimazole (Thiamazole) is a hepatotoxic antithyroid agent used to induce and study hyperthyroidism in experimental models. It is widely applied in both in vitro and in vivo research to investigate thyroid hormone synthesis, drug-induced liver injury, and autoimmune thyroid disease mechanisms.

Research Area

Metabolism Research

Images & Validation

Key Properties

CAS Number60-56-0
MW114.17
Purity99.21%
FormulaC4H6N2S
SMILESCN1C=CN=C1S
TargetThyroid hormone receptor(THR),Others
SolubilityH2O:21 mg/mL (183.94 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (17.52 mM);DMSO:60 mg/mL (525.53 mM);Ethanol:22 mg/mL (192.7 mM)

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

cytotoxicity, antithyroid, hepatotoxicity, hepatocytes, Inhibitor, Methimazole, inhibit, Tapazole, THR, Thiamazole, Thyroid hormone receptor, Thyroidhormonereceptor(THR), Thyroidhormonereceptor, Thyroid peripheral conversion, Thyroid hormone receptor(THR)

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Key Properties

No computed properties available.

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Methimazole (orb1310244)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

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200 mg
$ 70.00
1 ml x 10 mM (in DMSO)
$ 80.00
500 mg
$ 90.00
1 g
$ 100.00
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