Carbimazole

SKU: orb1310136

Description

Carbimazole

Research Area

Metabolism Research, Signal Transduction

Key Properties

• CAS Number: 22232-54-8
• MW: 186.23
• Purity: 99.98%
• Formula: C₇H₁₀N₂O₂S
• SMILES: C(OCC)(=O)N1C(=S)N(C)C=C1
• Target: p38 MAPK,Thyroid hormone receptor(THR)
• Solubility: Ethanol:12 mg/mL (64.44 mM);H2O:< 1 mg/mL (insoluble or slightly soluble);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (10.74 mM);DMSO:60 mg/mL (322.18 mM)

Bioactivity

• In Vivo:
  Once absorbed by the human body, Carbimazole is metabolized into Methimazole, which exerts anti-thyroid activity. It specifically targets conditions such as hyperthyroidism (excessive production of thyroid hormones) and thyrotoxicosis (thyroid inflammation).

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

antithyroid agent, Athyromazole, Carbimazol, Carbimazole, methimazole, MMI, Neomercazole, inhibit, Inhibitor, Graves' disease, THR, Thyroidhormonereceptor, Thyroidhormonereceptor(THR), Thyroid hormone receptor, Thyroid hormone receptor(THR), Thyroid peroxidase

Compound Identifiers

PubChem CID

31072