Mepivacaine hydrochloride

SKU: orb1310144

Description

Mepivacaine hydrochloride

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1722-62-9
• MW: 282.81
• Purity: 99.94%
• Formula: C₁₅H₂₂N₂O·HCl
• SMILES: Cl.CN1CCCCC1C(=O)Nc1c(C)cccc1C
• Target: Sodium Channel
• Solubility: H2O:52 mg/mL (183.87 mM);Ethanol:8 mg/mL (28.29 mM);DMSO:3 mg/mL (10.61 mM)

Bioactivity

• In Vivo:
  The tests made in horse show greater diffusion of mepivacaine between adjacent synovial structures than assumed from previous anatomical, latex injection and contrast arthrographic studies. Ultrasound provides a 37% reduction in the minimum effective anesthetic volume (MEAV50) of 1.5% mepivacaine required to block the sciatic nerve compared with neurostimulation in patients undergoing knee arthroscopy. The use of 3% mepivacaine provides a shorter duration of anesthesia than the lidocaine formulations with epinephrine in the canines and premolars.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

cell, depolarization, amide-type, anesthetic, Na channels, Na+ channels, neuronal, inhibit, infiltration, Mepivacaine, Mepivacaine HCl, Mepivacaine hydrochloride, Mepivacaine Hydrochloride, local, Inhibitor, regional, SodiumChannel, Sodium Channel

Compound Identifiers

PubChem CID

66070