Menin Antibody

• Catalog Number: orb1732498
• Category: Antibodies
• Description: Menin, the protein product of the MEN1 gene, is a component of the mixed-lineage leukemia protein (MLL)-containing histone methyltransferase complex that facilitates methylation of histone H3 Lys4 to promote transcriptional activation. Menin functions to suppress proliferation of pancreatic islet cells, at least in part through MLL-mediated activation of the p18INK4c (p18) and p27CIP/KIP (p27) cyclin-dependent kinase inhibitor genes.
• Species/Host: Rabbit
• Clonality: Monoclonal
• Tested applications: IP, WB
• Reactivity: Human, Rat
• Isotype: Rabbit IgG
• Immunogen: A synthetic peptide of human Menin
• Concentration: 1mg/ml
• Dilution range: IP: 1/20; WB: 1/500-1/1000
• Conjugation: Unconjugated
• MW: Calculated MW: 68 kDa; Observed MW: 68 kDa
• Entrez: 4221
• UniProt ID: O00255
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Buffer/Preservatives: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% rAlbumin
• Alternative names: MEN1; SCG2; Menin
• Note: For research use only
• Expiration Date: 12 months from date of receipt.