MD-265

SKU: orb2814521

Description

MD-265 is a PROTAC small molecule that induces MDM2 degradation, activating the p53 pathway in wild-type p53 cancer models. It has demonstrated potent anti-tumor activity, achieving complete tumor regression and enhancing survival in leukemic mouse models, supporting its use in oncology research.

Research Area

Cell Biology, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2415160-21-1
• MW: 921.88
• Formula: C₅₀H₅₁Cl₂FN₆O₆
• SMILES: O=C1[C@@]2(C3(N[C@@H](C(N[C@@H]4CC[C@@H](C(=O)N5CCC(C#CC6=C7C(C(=O)N(C7)C8C(=O)NC(=O)CC8)=CC=C6)CC5)CC4)=O)[C@@H]2C9=C(F)C(Cl)=CC=C9)CCCCC3)C=%10C(N1)=CC(Cl)=CC%10
• Target: PROTACs,MDM-2/p53

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

146461082