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MC-Val-Cit-PAB

SKU: orb1302049

Description

MC-Val-Cit-PAB is a protease-cleavable linker utilized in the construction of antibody-drug conjugates (ADCs), such as the clinically approved brentuximab vedotin. It enables targeted drug delivery and release in both in vitro and in vivo research models for oncology and targeted therapy development.

Research Area

Neuroscience, Signal Transduction

Images & Validation

Key Properties

CAS Number159857-80-4
MW572.65
Purity98.24% (May vary between batches)
FormulaC28H40N6O7
SMILES[C@@H](NC([C@@H](NC(CCCCCN1C(=O)C=CC1=O)=O)[C@H](C)C)=O)(C(NC2=CC=C(CO)C=C2)=O)CCCNC(N)=O
TargetAChR|||ADC Linker
SolubilityDMSO:22 mg/mL (38.42 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (8.73 mM)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

inhibit, Inhibitor, MCValCitPAB, MC-Val-Cit-PAB, MC Val Cit PAB, Antibody-drug conjugates linkers, ADCLinker, ADC Linker, ADC Linkers

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Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Protocol Information