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MAT2A inhibitor 5

SKU: orb2646277

Description

Compound 39 is a potent, selective, and orally bioavailable MAT2A inhibitor with an IC50 of 11 nM, capable of crossing the blood-brain barrier. It demonstrates robust antitumor efficacy in vivo, making it a valuable chemical probe for oncology research, particularly in studying methionine metabolism and tumor cell proliferation.

Research Area

Epigenetics & Chromatin

Images & Validation

Key Properties

CAS Number2957874-18-7
MW368.79
FormulaC19H14ClFN4O
SMILESO=C1C2=NN(C=C2C=3C=C(F)C(Cl)=CC3N1C4=CC=CN=C4C5CC5)C
TargetMethionine Adenosyltransferase (MAT)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

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Protocol Information

MAT2A inhibitor 5 (orb2646277)

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