Maprotiline hydrochloride

SKU: orb1227097

Description

Maprotiline is a tetracyclic antidepressant with similar pharmacological properties to tricyclic antidepressants (TCAs). Similar to TCAs, maprotiline inhibits neuronal norepinephrine reuptake, possesses some anticholinergic activity, and does not affect monoamine oxidase activity. It differs from TCAs in that it does not appear to block serotonin reuptake. Maprotiline may be used to treat depressive affective disorders, including dysthymic disorder (depressive neurosis) and major depressive disorder. Maprotiline is effective at reducing symptoms of anxiety associated with depression.

Key Properties

• CAS Number: 10347-81-6
• MW: 313.86
• Purity: >98% (HPLC)
• Formula: C₂₀H₂₄ClN
• SMILES: CNCCCC1(CC2)C3=CC=CC=C3C2C4=C1C=CC=C4.Cl
• Target: 5-HT Receptor
• Solubility: Ethanol: 24 mg/mL (76.46 mM); DMSO: 63 mg/mL (200.72 mM)

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Deprilept | Ludiomil

Quick Database Links

Gene Symbol

5-HT Receptor