MAPK-IN-2

SKU: orb2277845

Description

MAPK-IN-2 is a potent multi-kinase inhibitor targeting key oncogenic drivers including EGFR, B-RAF, c-MET, and CDK4/6. It demonstrates strong anti-proliferative activity in vitro against various cancer cell lines, particularly those harboring EGFR T790M and B-RAF V600E mutations, making it a valuable tool for cancer signaling pathway research.

Research Area

Signal Transduction

Key Properties

• MW: 380.23
• Formula: C₂₀H₁₁Cl₂N₃O
• SMILES: ClC1=CC=C(C(C=C(C2=CNC3=C2C=CC=C3)N4)=C(C#N)C4=O)C(Cl)=C1
• Target: CDK,c-Met/HGFR,Raf,p38 MAPK,EGFR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

168510404