NF-κB/MAPK-IN-2

SKU: orb2945845

Description

NF-κB/MAPK-IN-2 is a dual-pathway inhibitor that suppresses LPS-induced pro-inflammatory signaling by reducing phosphorylation of key proteins (p65, IκB, p38, JNK, ERK) and cytokine release (TNF-α, IL-6). It has demonstrated utility in cellular models of inflammation and shows research potential for investigating septic shock mechanisms.

Research Area

Signal Transduction

Key Properties

• CAS Number: 3070509-60-0
• MW: 827.056
• Formula: C₄₉H₆₆N₂O₉
• SMILES: CCOC(=O)C1=NOC2=C1C[C@]3([C@H]([C@]2(C)COC(=O)CCC(=O)N4CCOCC4)CC[C@@]5([C@@H]3CC=C6[C@]5(CC[C@@]7([C@H]6CC(CC7)(C)C)C(=O)OCC8=CC=CC=C8)C)C)C
• Target: NF-κB,p38 MAPK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

172676848