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Maleic acid

SKU: orb1302456

Description

Maleic acid acts as a glutamate decarboxylase (GAD) inhibitor in Listeria monocytogenes and Escherichia coli. This small molecule is used in research to study bacterial acid resistance mechanisms and GABA metabolism in both in vitro and in vivo experimental models.

Research Area

Infectious Disease & Virology, Metabolism Research

Images & Validation

Key Properties

CAS Number110-16-7
MW116.07
Purity97.44% (May vary between batches)
FormulaC4H4O4
SMILESOC(=O)\C=C/C(O)=O
TargetAntibacterial,Endogenous Metabolite
SolubilityDMSO:60 mg/mL (516.93 mM);H2O:80 mg/mL (689.24 mM)

Bioactivity

In Vitro
Of all compounds tested, Maleic Acid is the least inhibitory despite acting at a lower pH (4.84). The most acid resistant (10403S) and the weakest (EGD-e) strain are challenged with 8.6 mM and 4.3 mM of each organic acid at pH 3 and 3.3 respectively. On both strains, Maleic Acid is the most bactericidal.

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

E. coli, Bacterial, inhibit, Inhibitor, Maleic acid, Endogenous Metabolite, EndogenousMetabolite

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Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information

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200 mg
$ 70.00
DispatchUsually dispatched within 3-5 working days
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