Luliconazole

SKU: orb1305524

Description

Luliconazole (NND-502) is an azole antifungal agent that functions by inhibiting Cytochrome P450 2C19. It is widely used in research for studying antifungal mechanisms and resistance, with applications in both in vitro assays and in vivo models of dermatophyte and yeast infections.

Research Area

Infectious Disease & Virology

Key Properties

• CAS Number: 187164-19-8
• MW: 354.28
• Purity: 99.83% (May vary between batches)
• Formula: C₁₄H₉Cl₂N₃S₂
• SMILES: Clc1ccc([C@@H]2CS\C(S2)=C(\C#N)n2ccnc2)c(Cl)c1
• Target: Antifungal,Antibiotic
• Solubility: Ethanol:5 mg/mL (14.11 mM);DMSO:66 mg/mL (186.29 mM);H2O:< 1 mg/mL (insoluble or slightly soluble);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.65 mM)

Bioactivity

• In Vivo:
  Luliconazole inhibits the growth of all filamentous fungi (except Saccharomyces cerevisiae) (MIC,≦0.004-0.125 μg/ml), Candida albicans (MIC range: 0.031-0.13 mg/ml), Trichophyton rubrum (MIC,≦0.00012-0.002 mg/ml).
• In Vitro:
  Luliconazole inhibits the growth of all filamentous fungi (except Saccharomyces cerevisiae) (MIC,≦0.004-0.125 μg/ml), Candida albicans (MIC range: 0.031-0.13 mg/ml), Trichophyton rubrum (MIC,≦0.00012-0.002 mg/ml).

Storage & Handling

• Storage: keep away from moisture,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

skin infection, tinea corporis, tinea pedis, dermatophytosis, Antibiotic, antifungal, Antifungal, inhibit, LUZU, Luliconazole, NND 502, NND502, NND-502, Inhibitor, Fungal

Compound Identifiers

PubChem CID

3003141