LRP4 Antibody (RPE)

SKU: orb150138

Description

Mouse monoclonal to LRP4 (RPE). Potential cell surface endocytic receptor, which binds and internalizes extracellular ligands for degradation by lysosomes. It is involved in the negative regulation of the canonical Wnt signaling pathway, being able to antagonize the LRP6-mediated activation of this pathway..

Research Area

Metabolism Research

Images & Validation

• Tested Applications: ICC, IF, WB
• Dilution Range: WB (1:1000), ICC/IF (1:100)
• Reactivity: Human, Mouse, Rat
• Application Notes:
  1 µg/ml was sufficient for detection of LRP4 in 20 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

Key Properties

• Host: Mouse
• Clonality: Monoclonal
• Isotype: IgG2A
• Clone No.: N207/27 (Formerly sold as S207-27)
• Immunogen: Fusion protein amino acids 26- 350 (extracellular N-terminus) of mouse LTP4
• Target: LRP4
• Molecular Weight: 215kDa
• Purification: Protein G Purified
• Conjugation: RPE

Storage & Handling

• Storage: Conjugated antibodies should be stored according to the product label
• Buffer/Preservatives: 95.46mM Phosphate, 2.48mM MES and 2mM EDTA
• Concentration: 1 mg/ml
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

LRP4, LRP-4, LRP10, MEGF7, Low density lipoprotein receptor related protein 4, Multiple epidermal growth factor like domains 7, LDLR dan, LDLR, KIAA0816, Corin

Quick Database Links

Gene Symbol

LRP4

UniProt

Q8VI56

NCBI Gene ID

83469

RefSeq (Protein):NP_766256.3