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Lomitapide

SKU: orb1223221

Description

Lomitapide is a small molecule inhibitor of microsomal triglyceride transfer protein (MTP), an enzyme located in the lumen of the endoplasmic reticulum responsible for absorbing dietary lipids and transferring triglycerides onto apolipoprotein B (apo-B) in the assembly of very-low-density lipoprotein.

Images & Validation

Key Properties

CAS Number182431-12-5
MW692.71
Purity>98% (HPLC)
FormulaC39H37F6N3O2
SMILESc1cccc2c1C(c1c2cccc1)(CCCCN1CCC(CC1)NC(=O)c1c(cccc1)c1ccc(cc1)C(F)(F)F)C(=O)NCC(F)(F)F
TargetS6 Kinase
SolubilityDMSO : ≥ 35 mg/mL; 50.45 mM

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

AEGR-733 | BMS-201038

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Protocol Information

Lomitapide (orb1223221)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

2 mg
$ 110.00
5 mg
$ 160.00
10 mg
$ 220.00
25 mg
$ 340.00
50 mg
$ 480.00
100 mg
$ 700.00
200 mg
$ 990.00
500 mg
$ 1,510.00