Lirentelimab Antibody

SKU: orb1980575

Description

Lirentelimab (AK002) is a humanized monoclonal antibody targeting Siglec-8. It triggers apoptosis in activated eosinophils and inhibits mast cell activation, making it a research tool for studying conditions like systemic mastocytosis and allergic conjunctivitis. Its mechanisms have been investigated in both in vitro assays and in vivo preclinical models.

Research Area

Cell Biology

Images & Validation

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Key Properties

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Antibody Type	Inhibitor Antibody
Target	Apoptosis
Molecular Weight	144.55 kDa
Purity	97.70% (May vary between batches)
Conjugation	Unconjugated

Storage & Handling

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Storage	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Concentration	6.78 mg/mL
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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AK 002, AK002, Anti-Siglec-8 Reference Antibody, Antolimab, Apoptosis

Quality Guarantee

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Gene Symbol

Apoptosis

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