Liranaftate

SKU: orb1308449

Description

Liranaftate is a thiocarbamate antifungal agent that acts as a squalene epoxidase inhibitor. By blocking ergosterol synthesis and causing squalene accumulation, it disrupts fungal cell membrane integrity, leading to increased permeability and cell lysis. This mechanism supports its research use in studying antifungal activity in both in vitro and in vivo models.

Research Area

Infectious Disease & Virology, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 88678-31-3
• MW: 328.43
• Purity: 99.97% (May vary between batches)
• Formula: C₁₈H₂₀N₂O₂S
• SMILES: COc1cccc(n1)N(C)C(=S)Oc1ccc2CCCCc2c1
• Target: Antifungal
• Solubility: DMSO:9 mg/mL (27.4 mM);10% DMSO+90% Corn Oil:0.5 mg/mL (1.52 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

squalene, squalene epoxidase, Piritetrate, inhibit, Inhibitor, Liranaftate, IL-8, inflammation, M 732, M732, M-732, epoxidase, Fungal, dermatophytes, anti-fungal

Compound Identifiers

PubChem CID

3936