Liothyronine sodium

SKU: orb1224699

Description

Liothyronine Sodium is the most potent form of thyroid hormone acting on the body to increase the basal metabolic rate, affect protein synthesis.(In Vitro):Liothyronine (T3, 100 nM) sodium stimulates the proliferation of hepatocarcinema cells in which TRβ1 is overexpressed. Liothyronine sodium binds to human β1 thyroid hormone receptor (hTRβ1), and changes its conformation. Liothyronine sodium promotes growth, induces differentiation and regualtes metabolic effects.

Key Properties

• CAS Number: 55-06-1
• MW: 672.96
• Purity: >98% (HPLC)
• Formula: C₁₅H₁₁I₃NNaO₄
• SMILES: C1=CC(=C(C=C1OC2=C(C=C(C=C2I)C[C@@H](C(=O)[O-])N)I)I)O.[Na+]
• Target: THR
• Solubility: DMSO: 100 mg/mL (148.59 mM)

Bioactivity

• In Vitro:
  Liothyronine (T3, 100 nM) sodium stimulates the proliferation of hepatocarcinema cells in which TRβ1 is overexpressed. Liothyronine sodium binds to human β1 thyroid hormone receptor (hTRβ1), and changes its conformation. Liothyronine sodiumpromotes growth, induces differentiation and regualtes metabolic effects.

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Liothyronine | T3 | ??L-3,3',5-Triiodothyronine

Quick Database Links

Gene Symbol

THR