Licoisoflavone A

SKU: orb1684463

Description

Licoisoflavone A (Phaseoluteone) is a bioactive small molecule that functions as an MRP inhibitor and an antioxidant, exhibiting an IC50 of 7.2 μM against lipid peroxidation. It is utilized in research areas such as multidrug resistance and oxidative stress, with applications in both in vitro and in vivo experimental models.

Research Area

Cell Biology, Epigenetics & Chromatin, Immunology & Inflammation, Infectious Disease & Virology, Molecular Biology

Key Properties

• CAS Number: 66056-19-7
• MW: 354.35
• Purity: 99.71% (May vary between batches)
• Formula: C₂₀H₁₈O₆
• SMILES: CC(C)=CCc1c(O)ccc(c1O)-c1coc2cc(O)cc(O)c2c1=O
• Target: MRP
• Solubility: DMSO:90 mg/mL (253.99 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (9.31 mM)

Bioactivity

• In Vitro:
  Licoisoflavone A inhibits copper-induced protein oxidative modification of mice brain homogenate in vitro.

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

MRP, Licoisoflavone A, Phaseoluteone

Compound Identifiers

PubChem CID

5281789