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Catalog Number | orb1302792 |
---|---|
Category | Small Molecules |
Description | Licochalcone D |
CAS Number | 144506-15-0 |
Purity | 99.73% |
MW | 354.4 |
SMILES | C(=C/C(=O)C1=CC(CC=C(C)C)=C(O)C=C1)\C2=C(OC)C(O)=C(O)C=C2 |
Formula | C21H22O5 |
Biological Activity | Licochalcone D may be a potential drug for human melanoma treatment by inhibiting proliferation, inducing apoptosis via the mitochondrial pathway and blocking cell migration and invasion. Licochalcone D has cardioprotective potential against myocardial ischemia/reperfusion injury in langendorff-perfused rat hearts. Licochalcone D has anti-inflammatory activity, it shows suppression ability of nitric oxide (NO) production. Licochalcone D has anti-allergic activity, it suppresses degranulation by decreasing the intracellular Ca2+ level and tyrosine phosphorylation of ERK in RBL-2H3 cells. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
> 98% (HPLC) | |
144506-15-0 |
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